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Cellosaurus AtT-20/D16-16 (CVCL_GZ35)

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Cell line name AtT-20/D16-16
Accession CVCL_GZ35
Resource Identification Initiative To cite this cell line use: AtT-20/D16-16 (RRID:CVCL_GZ35)
Comments Characteristics: Produces adrenocorticotropic hormone (ACTH) (from parent cell line).
Transformant: NCIt; C17262; X-Ray.
Misspelling: AtT-20/D16-8; TOKU-E=3994.
Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
Disease Mouse pituitary gland neoplasms (NCIt: C24037)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: LAF1.
Hierarchy Parent: CVCL_4W08 (AtT-20/D16v)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=6250490; DOI=10.1016/0003-9861(80)90151-4
Steven L. Sabol;
Storage and secretion of beta-endorphin and related peptides by mouse pituitary tumor cells: regulation by glucocorticoids.
Arch. Biochem. Biophys. 203:37-48(1980)

PubMed=6300893; DOI=10.1073/pnas.80.7.2086; PMCID=PMC393758
Michael Adler, Brendan S. Wong, Steven L. Sabol, Neil Busis, Meyer B. Jackson, Forrest Fielding Weight Jr.;
Action potentials and membrane ion channels in clonal anterior pituitary cells.
Proc. Natl. Acad. Sci. U.S.A. 80:2086-2090(1983)

PubMed=2575458; DOI=10.1016/0143-4160(89)90024-9
Michael Adler, Steven L. Sabol, Neil Busis, Harish Chandra Pant;
Intracellular calcium and hormone secretion in clonal AtT-20/D16-16 anterior pituitary cells.
Cell Calcium 10:467-476(1989)

Cross-references
Cell line databases/resources TOKU-E; 3994
Encyclopedic resources Wikidata; Q54751296
Entry history
Entry creation26-Sep-2016
Last entry update14-Aug-2025
Version number9