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Cellosaurus MDCKts.src (CVCL_GZ12)

[Text version]
Cell line name MDCKts.src
Synonyms MDCKts.src, cl2; ts-src MDCK clone ts-31-2
Accession CVCL_GZ12
Resource Identification Initiative To cite this cell line use: MDCKts.src (RRID:CVCL_GZ12)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P00524; Rous sarcoma virus subgroup A (strain Schmidt-Ruppin) v-Src (Note=Rendered temperature sensitive).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
Hierarchy Parent: CVCL_0592 (MDCK-I)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=8425900; DOI=10.1083/jcb.120.3.757; PMCID=PMC2119534
Jurgen Behrens, Luc Vakaet, Robert Reaney Friis, Elke Winterhager, Frans M. Van Roy, Marc M. Mareel, Walter Birchmeier;
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.
J. Cell Biol. 120:757-766(1993)

Cross-references
Cell line databases/resources TOKU-E; 4072
Encyclopedic resources Wikidata; Q54904808
Entry history
Entry creation26-Sep-2016
Last entry update10-Sep-2024
Version number8