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Cellosaurus CAL-27 TPFR (CVCL_GY99)

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Cell line name CAL-27 TPFR
Accession CVCL_GY99
Resource Identification Initiative To cite this cell line use: CAL-27 TPFR (RRID:CVCL_GY99)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU).
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Leu (c.578A>T); ClinVar=VCV000185822; Zygosity=Unspecified (from parent cell line).
Disease Tongue adenosquamous carcinoma (NCIt: C173807)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1107 (CAL-27)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=25962396; DOI=10.3892/mmr.2015.3768
Sindhu Valiyaveedan Govindan, Safeena Kulsum, Ramanan Somasundara Pandian, Debashish Das, Mukund Seshadri, Wesley Hicks Jr., Moni Abraham Kuriakose, Amritha Suresh;
Establishment and characterization of triple drug resistant head and neck squamous cell carcinoma cell lines.
Mol. Med. Rep. 12:3025-3032(2015)

Cross-references
Encyclopedic resources Wikidata; Q54808395
Entry history
Entry creation26-Sep-2016
Last entry update19-Dec-2024
Version number15