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Cellosaurus CAL-27 TPFR (CVCL_GY99)

[Text version]
Cell line name CAL-27 TPFR
Accession CVCL_GY99
Resource Identification Initiative To cite this cell line use: CAL-27 TPFR (RRID:CVCL_GY99)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Selected for resistance to: ChEBI; CHEBI:4672; Docetaxel anhydrous (Taxotere).
Selected for resistance to: ChEBI; CHEBI:46345; 5-fluorouracil (5-FU).
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.His193Leu (c.578A>T); ClinVar=VCV000185822; Zygosity=Unspecified (from parent cell line).
Disease Tongue adenosquamous carcinoma (NCIt: C173807)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1107 (CAL-27)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=25962396; DOI=10.3892/mmr.2015.3768
Govindan S.V., Kulsum S., Pandian R.S., Das D., Seshadri M., Hicks W. Jr., Kuriakose M.A., Suresh A.
Establishment and characterization of triple drug resistant head and neck squamous cell carcinoma cell lines.
Mol. Med. Rep. 12:3025-3032(2015)

Cross-references
Encyclopedic resources Wikidata; Q54808395
Entry history
Entry creation26-Sep-2016
Last entry update29-Jun-2023
Version number14