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Cellosaurus KTOSA5 (CVCL_GY93)

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Cell line name KTOSA5
Accession CVCL_GY93
Resource Identification Initiative To cite this cell line use: KTOSA5 (RRID:CVCL_GY93)
Comments Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone, right hindlimb; UBERON=UBERON_0003464.
Disease Canine osteosarcoma (NCIt: C120045)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Rottweiler; VBO=VBO_0201143.
Sex of cell Female
Age at sampling 8Y
Category Cancer cell line
Publications

PubMed=24416158; DOI=10.1371/journal.pone.0083144; PMCID=PMC3885401
Lisa Y. Pang, Emma L. Gatenby, Ayako Kamida, Christopher Bruce Alexander Whitelaw, Ted R. Hupp, David John Argyle;
Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation.
PLoS ONE 9:e83144.1-e83144.13(2014)

PubMed=25190452; DOI=10.1186/s12917-014-0184-9; PMCID=PMC4172958
Lisa Y. Pang, Sally Anne Argyle, Ayako Kamida, Katherine O'Neill Morrison, David John Argyle;
The long-acting COX-2 inhibitor mavacoxib (Trocoxil TM) has anti-proliferative and pro-apoptotic effects on canine cancer cell lines and cancer stem cells in vitro.
BMC Vet. Res. 10:184.1-184.11(2014)

Cross-references
Encyclopedic resources Wikidata; Q54900665
Entry history
Entry creation26-Sep-2016
Last entry update10-Apr-2025
Version number9