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Cellosaurus T47D:C4:2 (CVCL_GY03)

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Cell line name T47D:C4:2
Synonyms T47D:C42; T47DC42; C4:2
Accession CVCL_GY03
Resource Identification Initiative To cite this cell line use: T47D:C4:2 (RRID:CVCL_GY03)
Comments Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_GY02 (T47D:C4)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=8883409; DOI=10.1038/bjc.1996.521; PMCID=PMC2075946
John J. Pink, Malcolm Maherji Bilimoria, Vasilios John Assikis, Virgil Craig Jordan;
Irreversible loss of the oestrogen receptor in T47D breast cancer cells following prolonged oestrogen deprivation.
Br. J. Cancer 74:1227-1236(1996)

Cross-references
Cell line databases/resources cancercelllines; CVCL_GY03
TOKU-E; 4085
Encyclopedic resources Wikidata; Q54971582
Entry history
Entry creation26-Sep-2016
Last entry update19-Dec-2024
Version number12