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Cellosaurus NI-1 [Dog mastocytoma] (CVCL_GT45)

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Cell line name NI-1 [Dog mastocytoma]
Accession CVCL_GT45
Resource Identification Initiative To cite this cell line use: NI-1 [Dog mastocytoma] (RRID:CVCL_GT45)
Comments Miscellaneous: Sex of donor from personal communication of Willmann, Michael.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Mast cell; CL=CL_0000097.
Sequence variations
  • Mutation; VGNC; VGNC:42422; KIT; Simple; p.Pro36Leu (c.107C>T); Zygosity=Unspecified (PubMed=22583069).
  • Mutation; VGNC; VGNC:42422; KIT; Simple; p.Gln396Arg (c.1187A>G); Zygosity=Unspecified (PubMed=22583069).
  • Mutation; VGNC; VGNC:42422; KIT; Simple; p.Glu417_Thr420dup (c.1249_1263dup); Zygosity=Unspecified (PubMed=22583069).
  • Mutation; VGNC; VGNC:42422; KIT; Simple; p.Gly513_Lys516del (c.1537_1548delGGTAACAGCAAG); Zygosity=Unspecified (PubMed=22583069).
Disease Canine mastocytoma (NCIt: C129077)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Mixed breed; VBO=VBO_0200902.
Sex of cell Male
Age at sampling 3-4Y
Category Cancer cell line
Publications

PubMed=22583069; DOI=10.1111/j.1398-9995.2012.02833.x; PMCID=PMC3401908
Emir Hadzijusufovic, Barbara Peter, Harald Herrmann, Thomas Rulicke, Sabine Cerny-Reiterer, Karina Schuch, Lukas Kenner, Tuddow Thaiwong, Vilma Yuzbasiyan-Gurkan, Winfried F. Pickl, Michael Willmann, Peter Valent;
NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation.
Allergy 67:858-868(2012)

Cross-references
Cell line collections (Providers) ABM; T8336
Encyclopedic resources Wikidata; Q54930542
Entry history
Entry creation26-Sep-2016
Last entry update10-Apr-2025
Version number10