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Cellosaurus PAZ6 (CVCL_GS29)

[Text version]
Cell line name PAZ6
Synonyms Paz6; PAZ-6
Accession CVCL_GS29
Resource Identification Initiative To cite this cell line use: PAZ6 (RRID:CVCL_GS29)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-1531.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brown adipose tissue; UBERON=UBERON_0001348.
Cell type: Preadipocyte; CL=CL_0002334.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Children
Category Transformed cell line
Publications

PubMed=9133667; DOI=10.1242/jcs.110.7.801
Vladimir Zilberfarb, France Pietri-Rouxel, Ralf Jockers, Stephane Krief, Claude Delouis, Tarik Issad, Arthur Donny Strosberg;
Human immortalized brown adipocytes express functional beta3-adrenoceptor coupled to lipolysis.
J. Cell Sci. 110:801-807(1997)

Patent=US6071747
Arthur Donny Strosberg, Vladimir Zilberfarb;
Immortalized cell lines from human adipose tissue, process for preparing same and applications thereof.
Patent number US6071747, 06-Jun-2000

PubMed=18283285; DOI=10.1038/ijo.2008.10
Esther Antoinette van Beek, Arjen H.F. Bakker, Philip M. Kruyt, Carolien Vink, Wim H.M. Saris, Nicole L.W. Franssen-van Hal, Jaap Keijer;
Comparative expression analysis of isolated human adipocytes and the human adipose cell lines LiSa-2 and PAZ6.
Int. J. Obes. 32:912-921(2008)

PubMed=22649407; DOI=10.3389/fendo.2012.00013; PMCID=PMC3355992
Melissa Kazantzis, Virginia Takahashi, Jessica Hinkle, Smitha Kota, Vladimir Zilberfarb, Tarik Issad, Mouaadh Abdelkarim, Lotfi Chouchane, Arthur Donny Strosberg;
PAZ6 cells constitute a representative model for human brown pre-adipocytes.
Front. Endocrinol. 3:13.1-13.9(2012)

PubMed=25925588; DOI=10.1186/s12967-015-0480-6; PMCID=PMC4438513
Andrea Guennoun, Melissa Kazantzis, Remy Thomas, Martin Wabitsch, Daniel Tews, Konduru Seetharama Sastry, Mouaadh Abdelkarim, Vladimir Zilberfarb, Arthur Donny Strosberg, Lotfi Chouchane;
Comprehensive molecular characterization of human adipocytes reveals a transient brown phenotype.
J. Transl. Med. 13:135.1-135.18(2015)

Cross-references
Cell line collections (Providers) ABM; T0729
Encyclopedic resources Wikidata; Q54938334
Gene expression databases GEO; GSM1543670
GEO; GSM1543671
Entry history
Entry creation26-Sep-2016
Last entry update14-Aug-2025
Version number13