Cellosaurus cell line XEMd-NH (CVCL

Cellosaurus XEMd-NH (CVCL_GR64)

Cross-references
Cell line name	XEMd-NH
Synonyms	XEMd.NH
Accession	CVCL_GR64
Resource Identification Initiative	To cite this cell line use: XEMd-NH (RRID:CVCL_GR64)
Comments	Genetic integration: Method=Transfection/transduction; Gene=RGD; 2459; Cyp1a2. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Lung; UBERON=UBERON_0002048. Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations	Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line). Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy	Parent: CVCL_4V38 (V79NH)
Sex of cell	Male
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=1793487; DOI=10.1002/mc.2940040613 Catherine Wolfel, Karl-Ludwig Platt, Satish Dogra, Hans-Ruedolf Glatt, Felix Wachter, Johannes Doehmer; Stable expression of rat cytochrome P450IA2 cDNA and hydroxylation of 17 beta-estradiol and 2-aminofluorene in V79 Chinese hamster cells. Mol. Carcinog. 4:489-498(1991) PubMed=1441600; DOI=10.3109/00498259209051863 Johannes Doehmer, Catherine Wolfel, Satish Dogra, C. Doehmer, Albrecht Seidel, Karl-Ludwig Platt, Franz Oesch, Hans-Ruedolf Glatt; Applications of stable V79-derived cell lines expressing rat cytochromes P4501A1, 1A2, and 2B1. Xenobiotica 22:1093-1099(1992)
Encyclopedic resources	Wikidata; Q54994670
Entry history
Entry creation	26-Sep-2016
Last entry update	14-Aug-2025
Version number	11