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Cellosaurus EO771 (CVCL_GR23)

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Cell line name EO771
Synonyms Eo771; E0771; EO 771
Accession CVCL_GR23
Resource Identification Initiative To cite this cell line use: EO771 (RRID:CVCL_GR23)
Comments Characteristics: Belongs to the luminal subtype B; ERalpha-, ERbeta+, PR+ and ErbB2+ (PubMed=32699527).
Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia, Gemma.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_A2HI (EO-NY)CVCL_C9CA (EO771-Luc)CVCL_B0A2 (EO771.lmb)
CVCL_VE17 (EO771E2)CVCL_D8G0 (Ubigene EO771 Ccl5 KO)CVCL_D8G1 (Ubigene EO771 Epha2 KO)
CVCL_D8G2 (Ubigene EO771 Fabp4 KO)CVCL_D8G3 (Ubigene EO771 Pik3ca KO)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
Mouse STR 1-117,18,19
Mouse STR 1-220,22
Mouse STR 2-116,18
Mouse STR 3-214,15
Mouse STR 4-221.3,22.3,24.3
Mouse STR 5-517,21,22
Mouse STR 6-418,19,20,21
Mouse STR 6-715,16
Mouse STR 7-125.2,26,26.2
Mouse STR 8-116
Mouse STR 11-215.3,16.3
Mouse STR 12-117,18
Mouse STR 13-117,18
Mouse STR 15-322.3,23.3
Mouse STR 17-215,16,17
Mouse STR 18-316,18
Mouse STR 19-213
Mouse STR X-127,29

Run an STR similarity search on this cell line
Web pages Provider; CH3 Biosystems; 940001; https://ch3biosystems.com/product/e0771/
Publications

PubMed=16312045
Andrew Ewens, Enrico Mihich, M. Jane Ehrke;
Distant metastasis from subcutaneously grown E0771 medullary breast adenocarcinoma.
Anticancer Res. 25:3905-3915(2005)

PubMed=24391448; DOI=10.7150/ijbs.6309; PMCID=PMC3879588
Su-He Wang, Lin Lu, Yong-Yi Fan, Max S. Wicha, Zheng-Yi Cao, Alfred E. Chang, Jian-Chuan Xia, James R. Baker Jr., Qiao Li;
Characterization of a novel transgenic mouse tumor model for targeting HER2+ cancer stem cells.
Int. J. Biol. Sci. 10:25-32(2013)

PubMed=32699527; DOI=10.1186/s12935-020-01418-1; PMCID=PMC7372867
Augustin Le Naour, Yvonne Koffi, Mariane Diab, Delphine Le Guennec, Stephanie Rouge, Sahar Aldekwer, Nicolas Goncalves-Mendes, Jeremie Talvas, Marie-Chantal Farges, Florence Caldefie-Chezet, Marie-Paule Vasson, Adrien Rossary;
EO771, the first luminal B mammary cancer cell line from C57BL/6 mice.
Cancer Cell Int. 20:328.1-328.13(2020)

PubMed=33026171; DOI=10.1002/cam4.3295; PMCID=PMC7643677
Augustin Le Naour, Adrien Rossary, Marie-Paule Vasson;
EO771, is it a well-characterized cell line for mouse mammary cancer model? Limit and uncertainty.
Cancer Med. 9:8074-8085(2020)

Cross-references
Cell line collections (Providers) ATCC; CRL-3461
Chemistry resources ChEMBL-Cells; CHEMBL4483168
ChEMBL-Targets; CHEMBL4483234
PubChem_Cell_line; CVCL_GR23
Encyclopedic resources Wikidata; Q54832331
Entry history
Entry creation26-Sep-2016
Last entry update14-Aug-2025
Version number13