Cellosaurus cell line ASAN-PaCa (CVCL

Cellosaurus ASAN-PaCa (CVCL_GP71)

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Cell line name

ASAN-PaCa

Synonyms

ASAN PaCa

Accession

CVCL_GP71

Resource Identification Initiative

To cite this cell line use: ASAN-PaCa (RRID:CVCL_GP71)

Comments

Problematic cell line: Contaminated. Shown to be a T3M-4 derivative (Direct_author_submission). Originally thought to originate from a 61 year old Caucasian female patient with a pancreatic intraductal papillary-mucinous carcinoma.
Population: Japanese.
Doubling time: 20 hours (PubMed=27518460).
Omics: Genomics; Whole exome sequencing.
Miscellaneous: STR profile and contamination by T3M-4 from personal communication of Giese, Nathalia A.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000177881; Zygosity=Heterozygous; Note=1 of 3 alleles (PubMed=27518460).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (PubMed=27518460).

Disease

Pancreatic ductal adenocarcinoma (NCIt: C9120)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_4056 (T3M-4)

Sex of cell

Male

Age at sampling

64Y

Category

Cancer cell line

STR profile

Source(s): Direct_author_submission

Markers:

Amelogenin	X
CSF1PO	10
D2S1338	17,25
D3S1358	14
D5S818	11
D7S820	11
D8S1179	16
D13S317	10,13
D16S539	11,12
D18S51	16
D19S433	14
D21S11	32.2,33.2
FGA	25,26
Penta D	10
Penta E	11,12
TH01	9.3
TPOX	11,12
vWA	18,19,21

Publications

PubMed=27518460; DOI=10.1097/MPA.0000000000000673
Anette Heller, Assia L. Angelova, Sonja Bauer, Svetlana P. Grekova, Marc Aprahamian, Jean Rommelaere, Michael Volkmar, Johannes W.G. Janssen, Nathalie Bauer, Ingrid Herr, Thomas Giese ...Show all 16 authors... , Matthias M. Gaida, Frank Bergmann, Thilo Hackert, Stefan Fritz, Nathalia A. Giese; Show fewer authors
Establishment and characterization of a novel cell line, ASAN-PaCa, derived from human adenocarcinoma arising in intraductal papillary mucinous neoplasm of the pancreas.
Pancreas 45:1452-1460(2016)

Cross-references

Cell line collections (Providers)

ABM; T8009 - Discontinued

Cell line databases/resources

cancercelllines; CVCL_GP71

Encyclopedic resources

Wikidata; Q54750668

Polymorphism and mutation databases

Cosmic; 2566118

Entry history

Entry creation

26-Sep-2016

Last entry update

14-Aug-2025

Version number