Cellosaurus cell line Nb2-Sp (CVCL

Cross-references
Cell line name	Nb2-Sp
Synonyms	Nb2-SP; NB2-Sp
Accession	CVCL_G706
Resource Identification Initiative	To cite this cell line use: Nb2-Sp (RRID:CVCL_G706)
Comments	Characteristics: Prolactin-independent (PubMed=3087389). Characteristics: Tumorigenic (PubMed=10214359).
Disease	Rat malignant lymphoma (NCIt: C60448)
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Nb.
Hierarchy	Parent: CVCL_G705 (Nb2)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=3087389; DOI=10.1139/o86-053 Harry P. Elsholtz, Robert P.C. Shiu, Henry George Friesen; Role of ornithine decarboxylase in proliferation of prolactin-dependent lymphoma cells. Biochem. Cell Biol. 64:381-386(1986) PubMed=1718958; DOI=10.1016/S0021-9258(18)54897-3 Suhad Ali, Isabelle Pellegrini, Paul A. Kelly; A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor. J. Biol. Chem. 266:20110-20117(1991) PubMed=10214359; DOI=10.1016/s0165-4608(98)00191-5 Catherine K.L. Too, Christine L.Y. Lee, Shirley M. Sangster, Peter Wilhelm Gout; Malignant progression of rat Nb2 lymphoma cells: chromosomal alterations and metastatic properties. Cancer Genet. Cytogenet. 110:115-123(1999)
Anatomy/cell type resources	BTO; BTO_0003057
Encyclopedic resources	Wikidata; Q54907523
Entry history
Entry creation	11-Feb-2013
Last entry update	27-Nov-2025
Version number	9