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Cellosaurus EB66 (CVCL_G703)

[Text version]
Cell line name EB66
Accession CVCL_G703
Resource Identification Initiative To cite this cell line use: EB66 (RRID:CVCL_G703)
Comments Group: Bird cell line.
Group: Patented cell line.
Group: Serum/protein free medium cell line.
Group: Vaccine production cell line.
From: Valneva SE; Saint-Herblain; France.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Anas platyrhynchos (Mallard) (Anas boschas) (NCBI Taxonomy: 8839)
Breed/subspecies: GL30; VBO=VBO_0017524.
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages Provider; Valneva SE; -; https://valneva.com/products/eb66-cell-line/
Publications

PubMed=20562528; DOI=10.4161/mabs.12350; PMCID=PMC3180087
Stephane Olivier, Marine Jacoby, Cedric Brillon, Sylvana Bouletreau, Thomas Mollet, Olivier Nerriere, Audrey Angel, Severine Danet, Boussad Souttou, Fabienne Guehenneux, Laurent Gauthier ...Show all 15 authors... , Mathilde Berthome, Henri Vie, Nicola Beltraminelli, Majid Mehtali; Show fewer authors
EB66 cell line, a duck embryonic stem cell-derived substrate for the industrial production of therapeutic monoclonal antibodies with enhanced ADCC activity.
MAbs 2:405-415(2010)

PubMed=21502045
Stephen W. Brown, Majid Mehtali;
The avian EB66(R) cell line, application to vaccines, and therapeutic protein production.
PDA J. Pharm. Sci. Technol. 64:419-425(2010)

PubMed=25903999; DOI=10.1002/biot.201400388
Yvonne Genzel;
Designing cell lines for viral vaccine production: where do we stand?
Biotechnol. J. 10:728-740(2015)

PubMed=26409141; DOI=10.1016/j.vaccine.2015.09.022
Takeshi Naruse, Tadashi Fukuda, Tetsuro Tanabe, Munetaka Ichikawa, Yoshiaki Oda, Shinji Tochihara, Kazuhiko Kimachi, Yoichiro Kino, Kohji Ueda;
A clinical phase I study of an EB66 cell-derived H5N1 pandemic vaccine adjuvanted with AS03.
Vaccine 33:6078-6084(2015)

Patent=US9260694
Fabienne Guehenneux, Karine Moreau, Magali Esnault, Majid Mehtali;
Generation of duck cell lines.
Patent number US9260694, 16-Feb-2016

Cross-references
Encyclopedic resources Wikidata; Q54831755
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number18