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Cellosaurus EB66 (CVCL_G703)

[Text version]
Cell line name EB66
Accession CVCL_G703
Resource Identification Initiative To cite this cell line use: EB66 (RRID:CVCL_G703)
Comments Group: Bird cell line.
Group: Patented cell line.
Group: Serum/protein free medium cell line.
Group: Vaccine production cell line.
From: Valneva SE; Saint-Herblain; France.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Anas platyrhynchos (Mallard) (Anas boschas) (NCBI Taxonomy: 8839)
Breed/subspecies: GL30.
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://web.archive.org/web/20180223230832/http://www.valneva.com/en/technologies/35

Olivier S., Jacoby M., Brillon C., Bouletreau S., Mollet T., Nerriere O., Angel A., Danet S., Souttou B., Guehenneux F., Gauthier L., Berthome M., Vie H., Beltraminelli N., Mehtali M.
EB66 cell line, a duck embryonic stem cell-derived substrate for the industrial production of therapeutic monoclonal antibodies with enhanced ADCC activity.
MAbs 2:405-415(2010)

Brown S.W., Mehtali M.
The avian EB66(R) cell line, application to vaccines, and therapeutic protein production.
PDA J. Pharm. Sci. Technol. 64:419-425(2010)

PubMed=25903999; DOI=10.1002/biot.201400388
Genzel Y.
Designing cell lines for viral vaccine production: where do we stand?
Biotechnol. J. 10:728-740(2015)

PubMed=26409141; DOI=10.1016/j.vaccine.2015.09.022
Naruse T., Fukuda T., Tanabe T., Ichikawa M., Oda Y., Tochihara S., Kimachi K., Kino Y., Ueda K.
A clinical phase I study of an EB66 cell-derived H5N1 pandemic vaccine adjuvanted with AS03.
Vaccine 33:6078-6084(2015)

Guehenneux F., Moreau K., Esnault M., Mehtali M.
Generation of duck cell lines.
Patent number US9260694, 16-Feb-2016

Encyclopedic resources Wikidata; Q54831755
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number16