• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=20149136).
  

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PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.
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Phosphoproteomic screen identifies potential therapeutic targets in melanoma.
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MicroRNA signatures differentiate melanoma subtypes.
Cell Cycle 10:1845-1852(2011)