Cellosaurus logo
expasy logo

Cellosaurus YUFIC (CVCL_G324)

[Text version]
Cell line name YUFIC
Accession CVCL_G324
Resource Identification Initiative To cite this cell line use: YUFIC (RRID:CVCL_G324)
Comments Part of: Yale University (YU) melanoma cell collection.
Omics: Genomics; Whole exome sequencing.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
Publications

PubMed=20149136; DOI=10.1111/j.1755-148X.2010.00685.x; PMCID=PMC2848976
Ruth Halaban, Wen-Geng Zhang, Antonella Bacchiocchi, Elaine Cheng, Fabio Parisi, Stephan Ariyan, Michael Krauthammer, James Patricia McCusker, Yuval Kluger, Mario Sznol;
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.
Pigment Cell Melanoma Res. 23:190-200(2010)

PubMed=21543894; DOI=10.4161/cc.10.11.15777; PMCID=PMC3233487
Elcie Chan, Rajeshvari Patel, Sunitha Nallur, Elena Ratner, Antonella Bacchiocchi, Kathleen Hoyt, Sebastian Szpakowski, Sirie E. Godshalk, Stephan Ariyan, Mario Sznol, Ruth Halaban ...Show all 15 authors... , Michael Krauthammer, David Tuck, Frank J. Slack, Joanne Barnes Weidhaas; Show fewer authors
MicroRNA signatures differentiate melanoma subtypes.
Cell Cycle 10:1845-1852(2011)

PubMed=26214590; DOI=10.1038/ng.3361; PMCID=PMC4916843
Michael Krauthammer, Yong Kong, Antonella Bacchiocchi, Perry Evans, Natapol Pornputtapong, Cen Wu, James Patricia McCusker, Shuang-Ge Ma, Elaine Cheng, Robert Straub, Merdan Serin ...Show all 20 authors... , Marcus W. Bosenberg, Stephan Ariyan, Deepak Narayan, Mario Sznol, Harriet Margot Kluger, Shrikant M. Mane, Joseph Schlessinger, Richard Priestley Lifton, Ruth Halaban; Show fewer authors
Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.
Nat. Genet. 47:996-1002(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_G324
Encyclopedic resources Wikidata; Q54995652
Polymorphism and mutation databases Cosmic; 1548853
Cosmic; 2439314
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number18