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Cellosaurus R6.5.D6.E9.B2 (CVCL_G148)

[Text version]
Cell line name R6.5.D6.E9.B2
Synonyms R6-5-D6
Accession CVCL_G148
Resource Identification Initiative To cite this cell line use: R6.5.D6.E9.B2 (RRID:CVCL_G148)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-9580.
Biotechnology: Was used to produce the monoclonal antibody enlimomab (BIRR-1) which is used in clinical trials in refractory rheumatoid arthritis and to reduce the incidence of acute rejection after kidney and liver allograft transplantations.
Monoclonal antibody isotype: IgG2a, kappa.
Monoclonal antibody target: UniProtKB; P05362; Human ICAM1/CD54.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_4032 (P3X63Ag8.653)
Category Hybridoma
Publications

Patent=US5284931
Timothy Alan Springer, Robert Rothlein, Steven D. Marlin, Michael L. Dustin;
Intercellular adhesion molecules, and their binding ligands.
Patent number US5284931, 08-Feb-1994

Patent=US5475091
Timothy Alan Springer, Robert Rothlein, Steven D. Marlin, Michael L. Dustin;
R6-5-D6, an antibody which binds intercellular adhesion molecule-1.
Patent number US5475091, 12-Dec-1995

Cross-references
Cell line collections (Providers) ATCC; HB-9580
BCRC; 60534
Cell line databases/resources CLO; CLO_0008719
Biological sample resources ABCD; ABCD_AH397
Encyclopedic resources Wikidata; Q54949057
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number11