Cellosaurus cell line HSC 62 (CVCL

Cellosaurus HSC 62 (CVCL_G046)

Cross-references
Cell line name	HSC 62
Synonyms	HSC-62; HSC62; GM13023
Accession	CVCL_G046
Secondary accession	CVCL_AK38
Resource Identification Initiative	To cite this cell line use: HSC 62 (RRID:CVCL_G046)
Comments	Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:1101; BRCA2; Simple; c.8488-1G>A (IVS19-1G>A); ClinVar=VCV000038164; Zygosity=Homozygous; Note=Splice acceptor mutation (PubMed=12065746).
Disease	Fanconi anemia, complementation group D1 (NCIt: C125705) Fanconi anemia (ORDO: Orphanet_84)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	2Y
Category	Transformed cell line
Publications	PubMed=6809308 Ryoji Ishida, Manuel Buchwald; Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents. Cancer Res. 42:4000-4006(1982) PubMed=7994019; DOI=10.1182/blood.V84.12.3995.bloodjournal84123995 Johnson M. Liu, Manuel Buchwald, Christopher Edward Walsh, Neal Stuart Young; Fanconi anemia and novel strategies for therapy. Blood 84:3995-4007(1994) PubMed=12065746; DOI=10.1126/science.1073834 Niall G. Howlett, Toshiyasu Taniguchi, Susan Olson, Barbara Cox, Quinten Waisfisz, Christine E.M. de Die-Smulders, Nicole Persky, Markus Grompe, Hans Joenje, Gerard Pals, Hideyuki Ikeda ...Show all 13 authors... , Edward A. Fox, Alan David D'Andrea; Show fewer authors Biallelic inactivation of BRCA2 in Fanconi anemia. Science 297:606-609(2002)
Cell line collections (Providers)	Coriell; GM13023
Cell line databases/resources	CLO; CLO_0013995
Biological sample resources	BioSample; SAMN00802020
Encyclopedic resources	Wikidata; Q54896374
Entry history
Entry creation	11-Feb-2013
Last entry update	19-Dec-2024
Version number	16