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Cellosaurus HSC 62 (CVCL_G046)

[Text version]
Cell line name HSC 62
Synonyms HSC-62; HSC62; GM13023
Accession CVCL_G046
Secondary accession CVCL_AK38
Resource Identification Initiative To cite this cell line use: HSC 62 (RRID:CVCL_G046)
Comments Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 1101; BRCA2; Simple; c.8488-1G>A (IVS19-1G>A); ClinVar=VCV000038164; Zygosity=Homozygous; Note=Splice acceptor mutation (PubMed=12065746).
Disease Fanconi anemia, complementation group D1 (NCIt: C125705)
Fanconi anemia (ORDO: Orphanet_84)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y
Category Transformed cell line
Publications

PubMed=6809308
Ishida R., Buchwald M.
Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents.
Cancer Res. 42:4000-4006(1982)

PubMed=7994019; DOI=10.1182/blood.V84.12.3995.bloodjournal84123995
Liu J.M., Buchwald M., Walsh C.E., Young N.S.
Fanconi anemia and novel strategies for therapy.
Blood 84:3995-4007(1994)

PubMed=12065746; DOI=10.1126/science.1073834
Howlett N.G., Taniguchi T., Olson S., Cox B., Waisfisz Q., de Die-Smulders C.E.M., Persky N., Grompe M., Joenje H., Pals G., Ikeda H., Fox E.A., D'Andrea A.D.
Biallelic inactivation of BRCA2 in Fanconi anemia.
Science 297:606-609(2002)

Cross-references
Cell line collections (Providers) Coriell; GM13023
Cell line databases/resources CLO; CLO_0013995
Biological sample resources BioSample; SAMN00802020
Encyclopedic resources Wikidata; Q54896374
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number15