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Cellosaurus RTC3 (CVCL_F760)

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Cell line name RTC3
Accession CVCL_F760
Resource Identification Initiative To cite this cell line use: RTC3 (RRID:CVCL_F760)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen (Note=With p.Leu156_Thr708del = T155g).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRSV-T155c).
Derived from site: In situ; Embryonic brain, ventral mesencephalon; UBERON=UBERON_0001943.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Sex of cell Sex unspecified
Age at sampling 14FD
Category Transformed cell line
Publications

PubMed=17708338; DOI=10.3727/000000007783464984; PMCID=PMC2494860
Brandon K. Harvey, Guann-Juh Chen, Cynthia J. Schoen, Chun-Ting Lee, Doug B. Howard, Ora Dillon-Carter, Mark Coggiano, William J. Freed, Yun Wang, Barry J. Hoffer, Joseph F. Sanchez;
An immortalized rat ventral mesencephalic cell line, RTC4, is protective in a rodent model of stroke.
Cell Transplant. 16:483-491(2007)

PubMed=22863662; DOI=10.1111/j.1582-4934.2012.01607.x; PMCID=PMC4118228
Asir Alwin Prem Anand, S. Gowri Sankar, Kokila V. Vani;
Immortalization of neuronal progenitors using SV40 large T antigen and differentiation towards dopaminergic neurons.
J. Cell. Mol. Med. 16:2592-2610(2012)

Cross-references
Encyclopedic resources Wikidata; Q54951383
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number16