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Cellosaurus BWTG3 (CVCL_F747)

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Cell line name BWTG3
Synonyms BW TG3
Accession CVCL_F747
Resource Identification Initiative To cite this cell line use: BWTG3 (RRID:CVCL_F747)
Comments Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57L/J.
Hierarchy Parent: CVCL_E4AK (BW)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=52568; DOI=10.1111/j.1432-0436.1975.tb01446.x
Cedric Szpirer, Josiane Szpirer;
A mouse hepatoma cell line which secretes several serum proteins including albumin and alpha-foetoprotein.
Differentiation 4:85-91(1975)

PubMed=3431441; DOI=10.1016/s0076-6879(87)51006-0
Gretchen J. Darlington;
Liver cell lines.
Methods Enzymol. 151:19-38(1987)

PubMed=1860901; DOI=10.1242/jcs.98.4.533
A.A. Farmer, Stephen John Goss;
BWTG3 hepatoma cells can acquire phenylalanine hydroxylase, cystathionine synthase and CPS-I without genetic manipulation, but activation of the silent OTC gene requires cell fusion with hepatocytes.
J. Cell Sci. 98:533-538(1991)

Cross-references
Cell line databases/resources CLO; CLO_0002064
CLDB; cl515
Encyclopedic resources Wikidata; Q54798740
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number10