Cellosaurus logo
expasy logo

Cellosaurus Hep3B GPC3-KO (CVCL_F6LB)

[Text][XML][JSON]
Cell line name Hep3B GPC3-KO
Synonyms KO13
Accession CVCL_F6LB
Resource Identification Initiative To cite this cell line use: Hep3B GPC3-KO (RRID:CVCL_F6LB)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4451; GPC3.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Miscellaneous: Cell line information from personal communication of Fayn, Stanley.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:903; AXIN1; Simple; p.Arg146Ter (c.436C>T); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Ser576Ter (c.1727C>G); Zygosity=Homozygous (from parent cell line).
Disease Childhood hepatocellular carcinoma (NCIt: C7955)
Pediatric hepatocellular carcinoma (ORDO: Orphanet_33402)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0326 (Hep 3B2.1-7)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
Entry history
Entry creation22-Oct-2026
Last entry update22-Oct-2026
Version number1