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Cellosaurus B78-D14 (CVCL_F6L2)

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Cell line name B78-D14
Accession CVCL_F6L2
Resource Identification Initiative To cite this cell line use: B78-D14 (RRID:CVCL_F6L2)
Comments Characteristics: Amelanotic.
Characteristics: Constitutively expresses GD2 and GD3 gangliosides (PubMed=8755561).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4117; B4GALNT1.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11410; ST8SIA1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03072; JC polyomavirus large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_F6L1 (KF3027-Hyg5)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8755561; DOI=10.1073/pnas.93.15.7826; PMCID=PMC38833
J.C. Becker, N. Varki, S.D. Gillies, K. Furukawa, R.A. Reisfeld;
An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response.
Proc. Natl. Acad. Sci. U.S.A. 93:7826-7831(1996)

Entry history
Entry creation22-Oct-2026
Last entry update22-Oct-2026
Version number1