Cellosaurus cell line KO_2 (CVCL

Entry history
Cell line name	KO_2
Synonyms	mNPC Parkin KO_2
Accession	CVCL_F6KR
Resource Identification Initiative	To cite this cell line use: KO_2 (RRID:CVCL_F6KR)
Comments	Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1355296; Prkn. Derived from site: In situ; Brain, forebrain; UBERON=UBERON_0001890. Cell type: Neural progenitor cell; CL=CL_0011020.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 Atrxfl/fl x B6.129S2-Trp53tm1Tyj/J.
Hierarchy	Parent: CVCL_F6KP (mNPC)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Finite cell line
Publications	PubMed=41959321; DOI=10.64898/2026.04.01.715918; PMCID=PMC13060259 Yongxing Gong, Armin Bayati, Tyler J. Alban, Prerana Parthasarathy, Fang Zhou, Vladimir Makarov, Yuhang Zhao, Chienwen Su, Jackson G. Schumacher, Vijay Singh, Laura A. Volpicelli-Daley ...Show all 18 authors... , Wen Luo, Thomas M. Durcan, Shovan Dutta, Michael A. Schwarzschild, Jennifer A. Johnston, Timothy A. Chan, Xiqun Chen; Show fewer authors Neural cell state modulation by PARK2 and dopaminergic neuroprotection by small molecule Parkin agonism. bioRxiv no_volume:2026.04.01.715918-2026.04.01.715918(2026)
Entry creation	22-Oct-2026
Last entry update	22-Oct-2026
Version number	1