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Cellosaurus EDITGENE SP7 Knockout U2OS Cell Line (CVCL_F6JD)

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Cell line name EDITGENE SP7 Knockout U2OS Cell Line
Synonyms SP7 Knockout U2OS Cell Line
Accession CVCL_F6JD
Resource Identification Initiative To cite this cell line use: EDITGENE SP7 Knockout U2OS Cell Line (RRID:CVCL_F6JD)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:17321; SP7.
Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC07588

Markers:
AmelogeninX
CSF1PO13
D1S165615,17.3
D2S133820,24
D3S135816
D5S81811
D6S104311
D7S82011,12
D8S117912,14
D12S39119,20
D13S31713
D16S53911,12
D18S5114
D19S43315
D21S1131
FGA20
Penta D9
Penta E10,13
TH016,9.3
TPOX11,12
vWA14,18

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Cross-references
Cell line collections (Providers) EDITGENE; EDC07588
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1