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Cellosaurus EDITGENE RXRA and RXRB Knockout A-549 Cell Line (CVCL_F6I4)

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Cell line name EDITGENE RXRA and RXRB Knockout A-549 Cell Line
Synonyms RXRA and RXRB Knockout A-549 Cell Line
Accession CVCL_F6I4
Resource Identification Initiative To cite this cell line use: EDITGENE RXRA and RXRB Knockout A-549 Cell Line (RRID:CVCL_F6I4)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10477; RXRA.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10478; RXRB.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC08241

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S44110,13
D2S133824
D3S135816
D5S81811
D6S104311,13
D7S8208,11
D8S117913,14
D12S39118
D13S31711
D16S53911,12
D18S5114,17
D19S43313
D21S1129
FGA23
Penta D9
Penta E7,11
TH018,9.3
TPOX8,11
vWA14

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Cross-references
Cell line collections (Providers) EDITGENE; EDC08241
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1