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Cellosaurus EDITGENE PALB2 Knockout BT-549 Cell Line (CVCL_F6HT)

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Cell line name EDITGENE PALB2 Knockout BT-549 Cell Line
Synonyms PALB2 Knockout BT-549 Cell Line
Accession CVCL_F6HT
Resource Identification Initiative To cite this cell line use: EDITGENE PALB2 Knockout BT-549 Cell Line (RRID:CVCL_F6HT)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:26144; PALB2.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Gene fusion; HGNC; HGNC:2092; CLTC + HGNC; HGNC:29559; VMP1; Name(s)=CLTC-VMP1 (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Val275fs*1 (c.821delG) (p.W274fs); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; c.265_607del343; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249Ser (c.747G>C); ClinVar=VCV000406598; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1092 (BT-549)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC90026

Markers:
AmelogeninX
CSF1PO10,12
D2S44111.3
D2S133817
D3S135818
D5S81811
D6S104311
D7S8209,10
D8S117914,16
D12S39118,20
D13S31711
D16S5398
D18S5115
D19S43315.2
D21S1132.2
FGA19
Penta D13
Penta E14
TH019.3
TPOX8
vWA15,18

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Cross-references
Cell line collections (Providers) EDITGENE; EDC90026
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1