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Cellosaurus EDITGENE CLK1 Knockout HAP1 Cell Line (CVCL_F6E8)

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Cell line name EDITGENE CLK1 Knockout HAP1 Cell Line
Synonyms CLK1 Knockout HAP1 Cell Line
Accession CVCL_F6E8
Resource Identification Initiative To cite this cell line use: EDITGENE CLK1 Knockout HAP1 Cell Line (RRID:CVCL_F6E8)
Comments Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:2068; CLK1.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_Y019 (HAP1)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC09085

Markers:
AmelogeninX
CSF1PO10
D1S165617.3
D2S44114
D2S133825
D3S135815
D5S81812
D7S8209
D8S11798,14
D10S124815
D12S39118
D13S31711
D16S53911
D18S5118
D19S43315
D21S1130
D22S104516
FGA21
Penta D9
Penta E10
TH017
TPOX8
vWA18

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Cross-references
Cell line collections (Providers) EDITGENE; EDC09085
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1