Cellosaurus cell line EDITGENE MDA-MB-231-CopGFP (CVCL

Cellosaurus EDITGENE MDA-MB-231-CopGFP (CVCL_F6B9)

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Cell line name

EDITGENE MDA-MB-231-CopGFP

Synonyms

MDA-MB-231-CopGFP

Accession

CVCL_F6B9

Resource Identification Initiative

To cite this cell line use: EDITGENE MDA-MB-231-CopGFP (RRID:CVCL_F6B9)

Comments

Population: Caucasian.
Characteristics: Growth mode Adherent.
Genetic integration: Method=Transduction; Gene=FPbase; 2BK6M; ppluGFP2 (copGFP, green fluorescent protein from P.plumata).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (from parent cell line).

Disease

Breast adenocarcinoma (NCIt: C5214)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0062 (MDA-MB-231)

Sex of cell

Female

Age at sampling

51Y