Cell line name |
SW732 |
Synonyms |
SW-732; SW 732 |
Accession |
CVCL_F651 |
Resource Identification Initiative |
To cite this cell line use: SW732 (RRID:CVCL_F651) |
Comments |
Problematic cell line: Contaminated. Shown to be a SW480 (or SW620) derivative (PubMed=288927; PubMed=20143388). Originally thought to originate from a 67 year old female patient with a cervical squamous cell carcinoma metastasized to the lung. From: Scott and White Clinic; Temple; USA. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00093. Population: Caucasian. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
|
HLA typing |
Source: PubMed=77569
Class I | HLA-A | A*02,09 | HLA-B | B*07,w22 | HLA-C | C*w03,w06 |
|
Disease |
Colon adenocarcinoma (NCIt: C4349) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0546 (SW480) |
Sex of cell |
Male |
Age at sampling |
51Y |
Category |
Cancer cell line |
Web pages |
Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx |
Publications | PubMed=327080; DOI=10.1093/jnci/59.1.221 Jorgen Fogh, Jens M. Fogh, Thomas Orfeo; One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J. Natl. Cancer Inst. 59:221-226(1977) PubMed=833871; DOI=10.1093/jnci/58.2.209 Jorgen Fogh, William C. Wright, James D. Loveless; Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J. Natl. Cancer Inst. 58:209-214(1977) PubMed=77569; DOI=10.1111/j.1399-0039.1978.tb01259.x Jons Ake Espmark, Lena Ahlqvist-Roth, Lena Sarne, Anita Persson; Tissue typing of cells in culture. III. HLA antigens of established human cell lines. Attempts at typing by the mixed hemadsorption technique. Tissue Antigens 11:279-286(1978) PubMed=288927; DOI=10.1093/jnci/63.3.635 Albert Leibovitz, William C. Wright, Sen Pathak, Michael Joseph Siciliano, Walter P. Daniels, Helle Fogh, Jorgen Fogh; Detection and analysis of a glucose 6-phosphate dehydrogenase phenotype B cell line contamination. J. Natl. Cancer Inst. 63:635-645(1979) PubMed=20143388; DOI=10.1002/ijc.25242 Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney; Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_F651
|
Biological sample resources |
BioSample; SAMN03151934
|
Encyclopedic resources |
Wikidata; Q54971200
|
Entry history |
Entry creation | 11-Feb-2013 |
Last entry update | 10-Apr-2025 |
Version number | 29 |
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