Cellosaurus cell line ITC-1 (CVCL

Cross-references
Cell line name	ITC-1
Accession	CVCL_F644
Resource Identification Initiative	To cite this cell line use: ITC-1 (RRID:CVCL_F644)
Comments	Characteristics: Produces glucagon (PubMed=1311428). Transformant: NCBI_TaxID; 1891762; BK polyomavirus (BKPyV). Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Disease	Hamster insulinoma (NCIt: C134946)
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Originate from same individual	CVCL_GR54 ! In-111-R1
Category	Cancer cell line
Publications	CLPUB00561 Toshio Hashiguchi, Mitsuko Hashiguchi, Saeko Sakai; Relationship between membrane potential change and glucagon secretion in a glucagon producing tumor cell line, ITC-1. J. Tokyo Med. Univ. 45:744-748(1987) PubMed=1311428; DOI=10.1007/BF00175473 Takefumi Miyazaki, Toshio Hashiguchi, Mitsuko Hashiguchi, Saeko Sakai, Tsuneo Tosaka, Minoru Kanazawa; Phenytoin partially antagonized L-type Ca2+ current in glucagon-secreting tumor cells (ITC-1). Naunyn Schmiedebergs Arch. Pharmacol. 345:78-84(1992) CLPUB00564 Shigehiko Suda; Heterogeneity and biological activity of glucagon extracted from glucagon producing tumor cells (ITC-1). Tokyo Ika Daigaku Zasshi 53:281-288(1995)
Encyclopedic resources	Wikidata; Q54898363
Entry history
Entry creation	11-Feb-2013
Last entry update	29-Jun-2023
Version number	7