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Cellosaurus EDITGENE ERCC2 (p.N238S) Point Mutation in 5637 Cell Line (CVCL_F5Y4)

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Cell line name EDITGENE ERCC2 (p.N238S) Point Mutation in 5637 Cell Line
Synonyms ERCC2 (p.N238S) Point Mutation in 5637 Cell Line
Accession CVCL_F5Y4
Resource Identification Initiative To cite this cell line use: EDITGENE ERCC2 (p.N238S) Point Mutation in 5637 Cell Line (RRID:CVCL_F5Y4)
Comments Characteristics: Growth mode Adherent.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:3434; ERCC2; Simple_edited; p.N238S; Zygosity=Unspecified; Note=By CRISPR/Cas9 (EDITGENE=EDC03193).
  • Mutation; HGNC; HGNC:6871; MAPK1; Simple; p.Arg79Lys (c.236G>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Tyr325Ter (c.975T>A); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Thr (c.839G>C); ClinVar=VCV000012368; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0126 (5637)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC03193

Markers:
AmelogeninX
CSF1PO11
D2S44114
D2S133825
D3S135815,17
D5S81811,12
D6S104316,20
D7S82010,11
D8S117910,16
D12S39120
D13S31711
D16S5399
D18S5116,18
D19S43313,15
D21S1136
FGA22
Penta D11
Penta E10,12
TH017,9
TPOX8
vWA18

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Cross-references
Cell line collections (Providers) EDITGENE; EDC03193
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1