Cellosaurus cell line EDITGENE HEC-1-B-FLUC (CVCL

Cellosaurus EDITGENE HEC-1-B-FLUC (CVCL_F5VG)

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Cell line name

EDITGENE HEC-1-B-FLUC

Synonyms

HEC-1-B-FLUC

Accession

CVCL_F5VG

Resource Identification Initiative

To cite this cell line use: EDITGENE HEC-1-B-FLUC (RRID:CVCL_F5VG)

Comments

Population: Japanese.
Characteristics: Growth mode Adherent.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:7329; MSH6; Simple; c.4001+1G>T; ClinVar=VCV001736936; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
Mutation; HGNC; HGNC:9122; PMS2; Simple; p.Arg802Ter (c.2404C>T); ClinVar=VCV000009237; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:9588; PTEN; None_reported; -; Zygosity=- (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).

Disease

Type II endometrial adenocarcinoma (NCIt: C39749)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0294 (HEC-1-B)

Sex of cell

Female

Age at sampling

71Y