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Cellosaurus EDITGENE NB4-Cas9 (CVCL_F5R0)

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Cell line name EDITGENE NB4-Cas9
Synonyms NB4-Cas9
Accession CVCL_F5R0
Resource Identification Initiative To cite this cell line use: EDITGENE NB4-Cas9 (RRID:CVCL_F5R0)
Comments Population: Caucasian.
Characteristics: Growth mode Suspension.
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:9113; PML + HGNC; HGNC:9864; RARA; Name(s)=PML-RARA (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Ala18Asp (c.53C>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Acute promyelocytic leukemia with PML-RARA (NCIt: C3182)
Acute promyelocytic leukemia (ORDO: Orphanet_520)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0005 (NB4)
Sex of cell Female
Age at sampling 23Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC01607

Markers:
AmelogeninX
CSF1PO11,12
D2S44110,14
D2S133820,25
D3S135815,17
D5S81813
D6S104312
D7S82010,13
D8S117910,14
D12S39119,22
D13S31711,12
D16S5399
D18S5112
D19S43315
D21S1128,33.2
FGA21,22
Penta D10,13
Penta E7,13
TH017,9.3
TPOX8,11
vWA16,19

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Cross-references
Cell line collections (Providers) EDITGENE; EDC01607
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1