Cellosaurus cell line EDITGENE SNCA Knockout H4 Cell Line (CVCL

Cross-references
Cell line name	EDITGENE SNCA Knockout H4 Cell Line
Synonyms	SNCA Knockout H4 Cell Line
Accession	CVCL_F5CC
Resource Identification Initiative	To cite this cell line use: EDITGENE SNCA Knockout H4 Cell Line (RRID:CVCL_F5CC)
Comments	Population: Caucasian. Characteristics: Growth mode Adherent. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11138; SNCA. Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:5382; IDH1; None_reported; -; Zygosity=- (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease	Astrocytoma (NCIt: C60781) Astrocytoma (ORDO: Orphanet_94)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1239 (H4)
Sex of cell	Male
Age at sampling	37Y
Category	Cancer cell line
Cell line collections (Providers)	EDITGENE; EDC07746
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1