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Cellosaurus EDITGENE MYC Knockout DMS273 Cell Line (CVCL_F5C4)

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Cell line name EDITGENE MYC Knockout DMS273 Cell Line
Synonyms MYC Knockout DMS273 Cell Line
Accession CVCL_F5C4
Resource Identification Initiative To cite this cell line use: EDITGENE MYC Knockout DMS273 Cell Line (RRID:CVCL_F5C4)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:7553; MYC.
Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:7910; NPM1; Simple; p.Asp173del (c.511_513delGAT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Cys (c.733G>T); ClinVar=VCV000012349; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1176 (DMS 273)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) EDITGENE; EDC07672
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1