Cellosaurus logo
expasy logo

Cellosaurus EDITGENE PTGER4 Knockout RT4 Cell Line (CVCL_F5BX)

[Text][XML][JSON]
Cell line name EDITGENE PTGER4 Knockout RT4 Cell Line
Synonyms PTGER4 Knockout RT4 Cell Line
Accession CVCL_F5BX
Resource Identification Initiative To cite this cell line use: EDITGENE PTGER4 Knockout RT4 Cell Line (RRID:CVCL_F5BX)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9596; PTGER4.
Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene fusion; HGNC; HGNC:3690; FGFR3 + HGNC; HGNC:11524; TACC3; Name(s)=FGFR3-TACC3 (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
  • Mutation; HGNC; HGNC:12362; TSC1; Simple; p.Leu557Cysfs*72 (c.1669delC); ClinVar=VCV000048811; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0036 (RT-4)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC07640

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S44110,13
D2S133818,19
D3S135815
D5S81811,12
D6S104313,19
D7S8209,12
D8S117913,15
D12S39120,22
D13S3178
D16S5399
D18S5115,17
D19S43313
D21S1130,32.2
FGA22,24
Penta D12,13
Penta E7,10
TH019,9.3
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Cross-references
Cell line collections (Providers) EDITGENE; EDC07640
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1