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Cellosaurus HyCyte A-549 stable cell line for hAPOBEC3B overexpression (CVCL_F4SC)

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Cell line name HyCyte A-549 stable cell line for hAPOBEC3B overexpression
Synonyms A-549 stable cell line for hAPOBEC3B overexpression
Accession CVCL_F4SC
Resource Identification Initiative To cite this cell line use: HyCyte A-549 stable cell line for hAPOBEC3B overexpression (RRID:CVCL_F4SC)
Comments Population: Caucasian.
Characteristics: Transfected with pPB[Exp]-Puro-TRE>InhAPOBEC3B[NM_004900.5].
Doubling time: 36-48 hours (Hysigen=CGSC-M33481).
Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:17352; APOBEC3B.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGSC-M33481
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1