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Cellosaurus HyCyte SU-DHL-4 stable cell line for hEBF1 overexpression (CVCL_F4P3)

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Cell line name HyCyte SU-DHL-4 stable cell line for hEBF1 overexpression
Synonyms SU-DHL-4 stable cell line for hEBF1 overexpression
Accession CVCL_F4P3
Resource Identification Initiative To cite this cell line use: HyCyte SU-DHL-4 stable cell line for hEBF1 overexpression (RRID:CVCL_F4P3)
Comments Population: Caucasian.
Characteristics: Transfected with pPB[Exp]-EF1A>luciferase-CAG>hEBF1[NM_024007.5]-PGK>puro.
Doubling time: 36-48 hours (Hysigen=CGSC-M29441).
Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:3126; EBF1.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Peritoneal effusion; UBERON=UBERON_0001268.
Sequence variations
  • Gene fusion; HGNC; HGNC:990; BCL2 + HGNC; HGNC:5477; IGH; Name(s)=IGH-BCL2 (from parent cell line).
  • Mutation; HGNC; HGNC:3527; EZH2; Simple; p.Tyr646Ser (c.1937A>C) (Y641S); ClinVar=VCV000376218; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:3527; EZH2; Simple; p.Tyr666Asn (c.1996T>A) (Y661N); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Homozygous (from parent cell line).
Disease Diffuse large B-cell lymphoma germinal center B-cell type (NCIt: C36080)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0539 (SU-DHL-4)
Sex of cell Male
Age at sampling 38Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGSC-M29441
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1