Cellosaurus cell line HyCyte U2OS hDARS2_ p.S242A_c.725A>G_c.724G>C cell line (CVCL

Cross-references
Cell line name	HyCyte U2OS hDARS2_ p.S242A_c.725A>G_c.724G>C cell line
Synonyms	hDARS2_ p.S242A_c.725A>G_c.724G>C cell line
Accession	CVCL_F4KK
Resource Identification Initiative	To cite this cell line use: HyCyte U2OS hDARS2_ p.S242A_c.725A>G_c.724G>C cell line (RRID:CVCL_F4KK)
Comments	Population: Caucasian. Doubling time: 18-24 hours (Hysigen=CGMU-M2275). Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations	Mutation; HGNC; HGNC:25538; DARS2; Simple_edited; p.S242A (NM_018122.5:c.725A>G NM_018122.5:c.724G>C); Zygosity=Homozygous (Hysigen=CGMU-M2275). Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease	Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0042 (U2OS)
Sex of cell	Female
Age at sampling	15Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGMU-M2275
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1