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Cellosaurus HyCyte MDA-MB-468 KO-hRALA (CVCL_F4HV)

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Cell line name HyCyte MDA-MB-468 KO-hRALA
Synonyms hRALA knockout MDA-MB-468 cell line
Accession CVCL_F4HV
Resource Identification Initiative To cite this cell line use: HyCyte MDA-MB-468 KO-hRALA (RRID:CVCL_F4HV)
Comments Population: African American.
Doubling time: 48-60 hours (Hysigen=CGKO-M2191).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; c.253+1G>T; ClinVar=VCV000189475; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; c.265_2787del2523; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0419 (MDA-MB-468)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2191
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1