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Cellosaurus HyCyte SK-OV-3 KO-hSIGLEC15 (CVCL_F4FA)

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Cell line name HyCyte SK-OV-3 KO-hSIGLEC15
Synonyms hSIGLEC15 knockout SK-OV-3 cell line
Accession CVCL_F4FA
Resource Identification Initiative To cite this cell line use: HyCyte SK-OV-3 KO-hSIGLEC15 (RRID:CVCL_F4FA)
Comments Population: Caucasian.
Doubling time: 48-60 hours (Hysigen=CGKO-M3381).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:27596; SIGLEC15.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M3381
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1