Cellosaurus cell line HyCyte MCF-7 KO-hWWP1 (CVCL

Cross-references
Cell line name	HyCyte MCF-7 KO-hWWP1
Synonyms	hWWP1 knockout MCF-7 cell line
Accession	CVCL_F4DP
Resource Identification Initiative	To cite this cell line use: HyCyte MCF-7 KO-hWWP1 (RRID:CVCL_F4DP)
Comments	Population: Caucasian. Doubling time: 36-48 hours (Hysigen=CGKO-M3287). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:17004; WWP1. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease	Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0031 (MCF-7)
Sex of cell	Female
Age at sampling	69Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M3287
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1