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Cellosaurus EPC2-EGFR (CVCL_F4C8)

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Cell line name EPC2-EGFR
Accession CVCL_F4C8
Resource Identification Initiative To cite this cell line use: EPC2-EGFR (RRID:CVCL_F4C8)
Comments Characteristics: Displays epithelial cell hyperproliferation and hyperplasia in organotypic cell culture.
Karyotypic information: Normal diploid karyotype (PubMed=12435727).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3236; EGFR.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Epithelium of esophagus; UBERON=UBERON_0001976.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F4C3 (EPC2)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Finite cell line
Publications

PubMed=12435727; DOI=10.1074/jbc.M209148200
Claudia D. Andl, Takaaki Mizushima, Hiroshi Nakagawa, Kenji Oyama, Hideki Harada, Katerina Chruma, Meenhard Herlyn, Anil K. Rustgi;
Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo.
J. Biol. Chem. 278:1824-1830(2003)

Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1