Cellosaurus cell line HyCyte SW620 KO-hHKDC1 (CVCL

Cross-references
Cell line name	HyCyte SW620 KO-hHKDC1
Synonyms	hHKDC1 knockout SW620
Accession	CVCL_F1TT
Resource Identification Initiative	To cite this cell line use: HyCyte SW620 KO-hHKDC1 (RRID:CVCL_F1TT)
Comments	Population: Caucasian. Doubling time: 36-48 hours (Hysigen=CGKO-M3064). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:23302; HKDC1. Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0547 (SW620)
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M3064
Entry history
Entry creation	27-Nov-2025
Last entry update	27-Nov-2025
Version number	1