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Cellosaurus (CVCL_F1TR)

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Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: MD Anderson Cell Lines Project.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Part of: UBC-40 urothelial bladder cancer cell line index.
Population: Caucasian.
Doubling time: 61 hours (PubMed=3708594); 46 hours (PubMed=25984343).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Phenotyping; shRNA library screening.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=12068308).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=24035680).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His365Arg (c.1094A>G); Zygosity=Unspecified (PubMed=7787250).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.12
East Asian, North1.86
East Asian, South0
South Asian0
European, North66.24
European, South31.77
Disease Recurrent bladder carcinoma (NCIt: C7899)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 44Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-1473; Cosmic-CLP=907065; ECACC=87032403; KCLB=21473; PubMed=11416159; PubMed=27270441

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133820,21
D3S135815,18
D5S81812
D7S82011,12
D8S11799,13
D13S31711,12
D16S53912,13
D18S5119
D19S43314,16
D21S1131,32.2
FGA20,23
Penta D9,12
Penta E10,11
TH016,9.3
TPOX11,12
vWA16,18

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Entry history
Entry creation04-Apr-2012
Last entry update31-Mar-2026
Version number46