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Cellosaurus HyCyte SH-SY5Y KO-hSV2A hSV2C (CVCL_F1TM)

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Cell line name HyCyte SH-SY5Y KO-hSV2A hSV2C
Synonyms hSV2A hSV2C knockout SH-SY5Y
Accession CVCL_F1TM
Resource Identification Initiative To cite this cell line use: HyCyte SH-SY5Y KO-hSV2A hSV2C (RRID:CVCL_F1TM)
Comments Population: Caucasian.
Doubling time: 48-60 hours (Hysigen=CGKO-M2836).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:20566; SV2A.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:30670; SV2C.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F1TL (HyCyte SH-SY5Y KO-hSV2A)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2836
Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1