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Cellosaurus HyCyte KGN KO-hYTHDC2 (CVCL_F1R6)

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Cell line name HyCyte KGN KO-hYTHDC2
Synonyms hYTHDC2 knockout KGN
Accession CVCL_F1R6
Resource Identification Initiative To cite this cell line use: HyCyte KGN KO-hYTHDC2 (RRID:CVCL_F1R6)
Comments Population: Japanese.
Doubling time: 18-24 hours (Hysigen=CGKO-M2758).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:24721; YTHDC2.
Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
Cell type: Granulosa cell; CL=CL_0000501.
Sequence variations
  • Mutation; HGNC; HGNC:1092; FOXL2; Simple; p.Cys134Trp (c.402C>G); ClinVar=VCV000376348; Zygosity=Heterozygous (from parent cell line).
Disease Ovarian granulosa cell tumor (NCIt: C6261)
Maligant granulosa cell tumor of the ovary (ORDO: Orphanet_99915)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0375 (KGN)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2758
Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1