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Cellosaurus HyCyte BT-549 KO-hBAD (CVCL_F1N3)

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Cell line name HyCyte BT-549 KO-hBAD
Synonyms hBAD knockout BT-549
Accession CVCL_F1N3
Resource Identification Initiative To cite this cell line use: HyCyte BT-549 KO-hBAD (RRID:CVCL_F1N3)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Doubling time: 36-48 hours (Hysigen=CGKO-M3283).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:936; BAD.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Gene fusion; HGNC; HGNC:2092; CLTC + HGNC; HGNC:29559; VMP1; Name(s)=CLTC-VMP1 (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Val275fs*1 (c.821delG) (p.W274fs); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; c.265_607del343; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249Ser (c.747G>C); ClinVar=VCV000406598; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1092 (BT-549)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M3283
Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1