Cellosaurus cell line HyCyte 5637 KO-hFGFR3 (CVCL

Cross-references
Cell line name	HyCyte 5637 KO-hFGFR3
Synonyms	hFGFR3 knockout 5637
Accession	CVCL_F1LN
Resource Identification Initiative	To cite this cell line use: HyCyte 5637 KO-hFGFR3 (RRID:CVCL_F1LN)
Comments	Doubling time: 24-36 hours (Hysigen=CGKO-M3061). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:3690; FGFR3. Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations	Mutation; HGNC; HGNC:6871; MAPK1; Simple; p.Arg79Lys (c.236G>A); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:9884; RB1; Simple; p.Tyr325Ter (c.975T>A); Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Thr (c.839G>C); ClinVar=VCV000012368; Zygosity=Homozygous (from parent cell line).
Disease	Bladder carcinoma (NCIt: C4912)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0126 (5637)
Sex of cell	Male
Age at sampling	68Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M3061
Entry history
Entry creation	27-Nov-2025
Last entry update	27-Nov-2025
Version number	1