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Cellosaurus UROtsa N6AMT1 (CVCL_F1K8)

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Cell line name UROtsa N6AMT1
Accession CVCL_F1K8
Resource Identification Initiative To cite this cell line use: UROtsa N6AMT1 (RRID:CVCL_F1K8)
Comments Characteristics: Transduced with a HEMK2(N6AMT1)-IRES-ZsGreen construct (PubMed=21193388).
Genetic integration: Method=Transduction; Gene=FPbase; W8LAG; ZsGreen (Note=FP506, green fluorescent protein derived from Zoanthus sp).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:16021; HEMK2.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Urinary bladder, urothelium; UBERON=UBERON_0004645.
Cell type: Urothelial cell; CL=CL_0000731.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0571 (UROtsa)
Sex of cell Female
Age at sampling 12Y
Category Transformed cell line
Publications

PubMed=21193388; DOI=10.1289/ehp.1002733; PMCID=PMC3114810
Xue-Feng Ren, Maria Alexandrovna Aleshin, William J. Jo, Russel Dills, David A. Kalman, Christopher D. Vulpe, Martyn T. Smith, Luo-Ping Zhang;
Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity.
Environ. Health Perspect. 119:771-777(2011)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1