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Cellosaurus HeLa GGA23-/- (CVCL_F1B9)

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Cell line name HeLa GGA23-/-
Accession CVCL_F1B9
Resource Identification Initiative To cite this cell line use: HeLa GGA23-/- (RRID:CVCL_F1B9)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:16064; GGA2.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:17079; GGA3.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F1B7 (HeLa GGA2-/-)
Children:
CVCL_F1BA (HeLa GGA123-/-)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=33206455; DOI=10.1002/2211-5463.13040; PMCID=PMC7876502
Balraj Doray, Lin Liu, Wang-Sik Lee, Benjamin C. Jennings, Stuart Arthur Kornfeld;
Inactivation of the three GGA genes in HeLa cells partially compromises lysosomal enzyme sorting.
FEBS Open Bio 11:367-374(2021)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1