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Cellosaurus CS-1/PR (CVCL_F1B3)

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Cell line name CS-1/PR
Synonyms CS-1/Zal
Accession CVCL_F1B3
Resource Identification Initiative To cite this cell line use: CS-1/PR (RRID:CVCL_F1B3)
Comments Population: Caucasian.
Characteristics: Exhibits cross resistance to cisplatin and methotrexate but not to doxorubicin (PubMed=19742314).
Selected for resistance to: ChEBI; CHEBI_235523; Zalypsis (PM00104).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Bone, humerus; UBERON=UBERON_0000976.
Disease Chondrosarcoma (NCIt: C2946)
Chondrosarcoma (ORDO: Orphanet_55880)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_T023 (CS-1 [Human chondrosarcoma])
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=19742314; DOI=10.1371/journal.pone.0006967; PMCID=PMC2734182
Zhen-Feng Duan, Edwin Choy, David C. Harmon, Cao Yang, Keinosuke Ryu, Joseph H. Schwab, Henry J. Mankin, Francis John Hornicek;
ZNF93 increases resistance to ET-743 (Trabectedin; Yondelis) and PM00104 (Zalypsis) in human cancer cell lines.
PLoS ONE 4:e6967.1-e6967.10(2009)

Cross-references
Gene expression databases GEO; GSM419914
Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1